Antibody

Quest Diagnostics

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COVID-19

Quest Diagnostics

Antibody blood test

Antibody Test Illustration

This type of test detects antibodies that show whether you have already recovered from a prior COVID-19 infection—even if you never showed signs of being sick. The presence of antibodies indicates you may possibly have a lower risk of COVID-19 reinfection.* Understanding your antibody status and risk level helps you and your doctor or healthcare provider make an informed decision about returning to work or activity.

Did you know? More than 9 million COVID-19 tests have been performed worldwide, but there have been no confirmed cases of reinfection. More research is needed, but this points to the risk of reinfection being very low.*

Who can get tested: Antibody testing is available only to patients who are not currently experiencing COVID-19 symptoms and have not experienced symptoms within 10 days. Common COVID-19 symptoms include fever, cough, and shortness of breath.

How the test works: If your doctor or healthcare provider has submitted an order for you to get a COVID-19 antibody test or you purchased one through QuestDirect, you can make an appointment at a Quest patient service center. You do not need to fast for this test. A phlebotomist will draw your blood, and the specimen is then sent to Quest laboratories for processing.

Where to get tested: You can make an appointment at a Quest patient service center for an antibody test. However, your doctor or healthcare provider must have submitted an order for your test or you must have purchased one through QuestDirect.

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What you need to KNOW about antibody tests

COVID-19 antibody tests have the potential to play a critical role in helping our communities move forward. Discover how this test option can tell us more about the virus and give us the insights we need to help stop its spread.

 

Getting test results through MyQuest

When you get an antibody test at a Quest patient service center, your test results can be sent to you automatically through the secure MyQuest online portal. This is usually the quickest way to get results.

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*The role of antibodies in preventing COVID-19 reinfection has yet to be established. With more than 9 million tests performed worldwide as of June 2020, there have been no confirmed cases of reinfection (Quest Diagnostics, Data on File, June 2020). Antibody testing for other respiratory illnesses (SARS-1, flu) also provides insight into possible future reinfection.

Important information about COVID-19 antibody testing

The test is designed to detect antibodies to SARS-CoV-2, the virus that causes COVID-19. Antibodies are proteins that the body produces in response to infections. The antibodies can be produced even if a person has few or no symptoms during the infection.

It generally takes some time after infection for antibodies to be produced and become detectable in blood (sometimes up to 3 weeks). It is important to remember that we do not yet know whether having antibodies to SARS-CoV-2 will prevent against getting the infection again or if you are totally free of the virus. Antibodies are generally detectable in the blood for a period of time after a person has recovered from the infection and after the virus that caused the infection is no longer detectable by laboratory methods.

Sometimes the antibodies developed in response to an infection protect us from getting that same infection again. But, it is important to know that we do not yet know whether this is true for COVID-19. Even if you have recovered and have antibodies, there is a chance that you still have the virus and you can infect others, it is still critical to keep taking measures to avoid getting infected again and/or spreading infection.

The antibody test is not meant for detecting an active infection. The swab test (sometimes also known as a molecular, RNA or PCR test) should be used to test for active infection.

A negative antibody test result means that antibodies were not detected in your blood sample. This can have several possible meanings. It could mean that:

  • You have not been infected with SARS-CoV-2, or
  • You have been infected with SARS-CoV-2, but your antibodies have not reached a sufficient level for the test to be able to detect them, or
  • You have been infected with SARS-CoV-2, but there has not been enough time for antibodies to develop (it can take up to one to three weeks to develop antibodies after someone is infected, sometimes longer).

A positive antibody test result means that antibodies were detected in your blood sample. This can have a couple of possible meanings. It could mean that:

  • You have been infected with SARS-CoV-2 at some point in the past, or
  • Uncommonly, you may have developed antibodies from an earlier infection with a different virus related to SARS-CoV-2 and the laboratory test cannot distinguish between these other virus antibodies and those antibodies generated in response to SARS-CoV-2.

COVID-19 testing statements

  • The antibody tests and the molecular tests (together “All tests”) have not been FDA cleared or approved;
  • All tests have been authorized by FDA under EUAs for use by authorized laboratories;
  • The antibody tests have been authorized only for the detection of IgG antibodies against SARS-CoV-2, not for any other viruses or pathogens;
  • The molecular tests have been authorized only for the detection of nucleic acid from SARS-CoV-2, not for any other viruses, pathogens; and,
  • All tests are only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostics for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Act, 21 U.S.C. § 360bbb-3(b)(1), unless the authorization is terminated or revoked sooner.